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Multivalent interactions between molecular components involved in fast endophilin mediated endocytosis drive protein phase separation

A specific group of transmembrane receptors, including the β1-adrenergic receptor (β1-AR), is internalized through a non-clathrin pathway known as Fast Endophilin Mediated Endocytosis (FEME). A key question is: how does the endocytic machinery assemble and how is it modulated by activated receptors...

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Detalles Bibliográficos
Autores principales: Mondal, Samsuzzoha, Narayan, Karthik, Botterbusch, Samuel, Powers, Imania, Zheng, Jason, James, Honey Priya, Jin, Rui, Baumgart, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418313/
https://www.ncbi.nlm.nih.gov/pubmed/36028485
http://dx.doi.org/10.1038/s41467-022-32529-0