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Task-dependent learning and memory deficits in the TgF344-AD rat model of Alzheimer’s disease: three key timepoints through middle-age in females

The TgF344 rat model of Alzheimer’s disease (AD) provides a comprehensive neuropathology presentation, with age-dependent development of tau tangles, amyloid-beta (A[Formula: see text] ) plaques, neuronal loss, and increased gliosis. The behavioral trajectory of this model, particularly relating to...

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Detalles Bibliográficos
Autores principales: Bernaud, Victoria E., Bulen, Haidyn L., Peña, Veronica L., Koebele, Stephanie V., Northup-Smith, Steven N., Manzo, Alma A., Valenzuela Sanchez, Maria, Opachich, Zorana, Ruhland, Ashley M., Bimonte-Nelson, Heather A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418316/
https://www.ncbi.nlm.nih.gov/pubmed/36028737
http://dx.doi.org/10.1038/s41598-022-18415-1