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Specificity of the Hox member Deformed is determined by transcription factor levels and binding site affinities
Hox proteins have similar binding specificities in vitro, yet they control different morphologies in vivo. This paradox has been partially solved with the identification of Hox low-affinity binding sites. However, anterior Hox proteins are more promiscuous than posterior Hox proteins, raising the qu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418327/ https://www.ncbi.nlm.nih.gov/pubmed/36028502 http://dx.doi.org/10.1038/s41467-022-32408-8 |