A conserved domain of Drosophila RNA-binding protein Pumilio interacts with multiple CCR4–NOT deadenylase complex subunits to repress target mRNAs

Pumilio is a sequence-specific RNA-binding protein that controls development, stem cell fate, and neurological functions in Drosophila. Pumilio represses protein expression by destabilizing target mRNAs in a manner dependent on the CCR4–NOT deadenylase complex. Three unique repression domains in the...

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Detalles Bibliográficos
Autores principales: Haugen, Rebecca J., Arvola, René M., Connacher, Robert P., Roden, Richard T., Goldstrohm, Aaron C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418443/
https://www.ncbi.nlm.nih.gov/pubmed/35850301
http://dx.doi.org/10.1016/j.jbc.2022.102270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418443/
https://www.ncbi.nlm.nih.gov/pubmed/35850301
http://dx.doi.org/10.1016/j.jbc.2022.102270

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