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Interaction of the motor protein SecA and the bacterial protein translocation channel SecYEG in the absence of ATP

Translocation of many secretory proteins through the bacterial plasma membrane is facilitated by a complex of the SecYEG channel with the motor protein SecA. The ATP-free complex is unstable in detergent, raising the question how SecA may perform several rounds of ATP hydrolysis without being releas...

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Detalles Bibliográficos
Autores principales: Winkler, Klemens, Karner, Andreas, Horner, Andreas, Hannesschlaeger, Christof, Knyazev, Denis, Siligan, Christine, Zimmermann, Mirjam, Kuttner, Roland, Pohl, Peter, Preiner, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418451/
https://www.ncbi.nlm.nih.gov/pubmed/36134293
http://dx.doi.org/10.1039/d0na00427h