Myosin light chain phosphatase catalytic subunit dephosphorylates cardiac myosin via mechanisms dependent and independent of the MYPT regulatory subunits

Cardiac muscle myosin regulatory light chain (RLC) is constitutively phosphorylated at ∼0.4 mol phosphate/mol RLC in normal hearts, and phosphorylation is maintained by balanced activities of dedicated cardiac muscle–specific myosin light chain kinase and myosin light chain phosphatase (MLCP). Previ...

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Detalles Bibliográficos
Autores principales: Lee, Eunyoung, Liu, Zhenan, Nguyen, Nhu, Nairn, Angus C., Chang, Audrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418503/
https://www.ncbi.nlm.nih.gov/pubmed/35872014
http://dx.doi.org/10.1016/j.jbc.2022.102296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418503/
https://www.ncbi.nlm.nih.gov/pubmed/35872014
http://dx.doi.org/10.1016/j.jbc.2022.102296

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