Cargando…

Results From Drug–Drug Interaction Studies In Vitro and In Vivo Investigating the Inhibitory Effect of Finerenone on the Drug Transporters BCRP, OATP1B1, and OATP1B3

BACKGROUND AND OBJECTIVES: In vitro and in vivo studies were performed with the novel, selective, nonsteroidal mineralocorticoid receptor antagonist finerenone to assess the relevance of inhibitory effects on the transporters breast cancer resistance protein (BCRP), organic anion transporting polype...

Descripción completa

Detalles Bibliográficos
Autores principales: Heinig, Roland, Fricke, Robert, Wertz, Sebastian, Nagelschmitz, Johannes, Loewen, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418647/
https://www.ncbi.nlm.nih.gov/pubmed/36029368
http://dx.doi.org/10.1007/s13318-022-00794-5