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Results From Drug–Drug Interaction Studies In Vitro and In Vivo Investigating the Inhibitory Effect of Finerenone on the Drug Transporters BCRP, OATP1B1, and OATP1B3
BACKGROUND AND OBJECTIVES: In vitro and in vivo studies were performed with the novel, selective, nonsteroidal mineralocorticoid receptor antagonist finerenone to assess the relevance of inhibitory effects on the transporters breast cancer resistance protein (BCRP), organic anion transporting polype...
Autores principales: | Heinig, Roland, Fricke, Robert, Wertz, Sebastian, Nagelschmitz, Johannes, Loewen, Stephanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418647/ https://www.ncbi.nlm.nih.gov/pubmed/36029368 http://dx.doi.org/10.1007/s13318-022-00794-5 |
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