Magel2 knockdown in hypothalamic POMC neurons innervating the medial amygdala reduces susceptibility to diet-induced obesity

Hyperphagia and obesity profoundly affect the health of children with Prader–Willi syndrome (PWS). The Magel2 gene among the genes in the Prader–Willi syndrome deletion region is expressed in proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC). Knockout of the Magel2...

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Detalles Bibliográficos
Autores principales: Choi, Yuna, Min, Hyeon-Young, Hwang, Jiyeon, Jo, Young-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418835/
https://www.ncbi.nlm.nih.gov/pubmed/36007929
http://dx.doi.org/10.26508/lsa.202201502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418835/
https://www.ncbi.nlm.nih.gov/pubmed/36007929
http://dx.doi.org/10.26508/lsa.202201502

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