Regenerative medicine meets translational oncology: Modeling leukemic bone marrow niche

Most studies on leukemia focus on leukemia cells as isolated objects without considering the bone marrow niche. Pal et al. have recreated the bone marrow niche using induced pluripotent stem cells (iPSCs), identifying CDH2 as a therapeutically druggable leukemia-promoting factor.(1)

Detalles Bibliográficos
Autores principales: Borbaran-Bravo, Natalia, Arreba-Tutusaus, Patricia, Ritter, Malte U., Nasri, Masoud, Klimiankou, Maksim, Skokowa, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418842/
https://www.ncbi.nlm.nih.gov/pubmed/35977470
http://dx.doi.org/10.1016/j.xcrm.2022.100724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418842/
https://www.ncbi.nlm.nih.gov/pubmed/35977470
http://dx.doi.org/10.1016/j.xcrm.2022.100724

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