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Hemagglutinin stalk-binding antibodies enhance effectiveness of neuraminidase inhibitors against influenza via Fc-dependent effector functions

The conserved hemagglutinin stalk domain is an attractive target for broadly effective antibody-based therapeutics and next-generation universal influenza vaccines. Protection provided by hemagglutinin stalk-binding antibodies is principally mediated through activation of immune effector cells. Tite...

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Detalles Bibliográficos
Autores principales: Zhang, Ali, Chaudhari, Hanu, Agung, Yonathan, D’Agostino, Michael R., Ang, Jann C., Tugg, Yona, Miller, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418849/
https://www.ncbi.nlm.nih.gov/pubmed/35977467
http://dx.doi.org/10.1016/j.xcrm.2022.100718