Lack of xanthine dehydrogenase leads to a remarkable renal decline in a novel hypouricemic rat model

Uric acid (UA) is the final metabolite in purine catabolism in humans. Previous studies have shown that the dysregulation of UA homeostasis is detrimental to cardiovascular and kidney health. The Xdh gene encodes for the Xanthine Oxidoreductase enzyme group, responsible for producing UA. To explore...

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Detalles Bibliográficos
Autores principales: Dissanayake, Lashodya V., Zietara, Adrian, Levchenko, Vladislav, Spires, Denisha R., Burgos Angulo, Mariana, El-Meanawy, Ashraf, Geurts, Aron M., Dwinell, Melinda R., Palygin, Oleg, Staruschenko, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418856/
https://www.ncbi.nlm.nih.gov/pubmed/36039296
http://dx.doi.org/10.1016/j.isci.2022.104887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418856/
https://www.ncbi.nlm.nih.gov/pubmed/36039296
http://dx.doi.org/10.1016/j.isci.2022.104887

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