Cargando…
Lack of xanthine dehydrogenase leads to a remarkable renal decline in a novel hypouricemic rat model
Uric acid (UA) is the final metabolite in purine catabolism in humans. Previous studies have shown that the dysregulation of UA homeostasis is detrimental to cardiovascular and kidney health. The Xdh gene encodes for the Xanthine Oxidoreductase enzyme group, responsible for producing UA. To explore...
Autores principales: | Dissanayake, Lashodya V., Zietara, Adrian, Levchenko, Vladislav, Spires, Denisha R., Burgos Angulo, Mariana, El-Meanawy, Ashraf, Geurts, Aron M., Dwinell, Melinda R., Palygin, Oleg, Staruschenko, Alexander |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418856/ https://www.ncbi.nlm.nih.gov/pubmed/36039296 http://dx.doi.org/10.1016/j.isci.2022.104887 |
Ejemplares similares
-
Modulation of blood pressure regulatory genes in the Agtrap‐Plod1 locus associated with a deletion in Clcn6
por: Klemens, Christine A., et al.
Publicado: (2022) -
Characterization of purinergic receptor 2 signaling in podocytes from diabetic kidneys
por: Palygin, Oleg, et al.
Publicado: (2021) -
Role of opioid signaling in kidney damage during the development of salt-induced hypertension
por: Golosova, Daria, et al.
Publicado: (2020) -
Effects of elevation of ANP and its deficiency on cardiorenal function
por: Ilatovskaya, Daria V., et al.
Publicado: (2022) -
Evaluation of Xanthine Oxidase Inhibitory Potential and In vivo Hypouricemic Activity of Dimocarpus longan Lour. Extracts
por: Sheu, Shi-Yuan, et al.
Publicado: (2016)