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Human protein arginine methyltransferases (PRMTs) can be optimally active under nonphysiological conditions

Protein arginine methylation is involved in many biological processes and can be enhanced in cancer. In mammals, these reactions are catalyzed on multiple substrates by a family of nine protein arginine methyltransferases (PRMTs). However, conditions that may regulate the activity of each enzyme and...

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Detalles Bibliográficos
Autores principales: Lowe, Troy L., Clarke, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418908/
https://www.ncbi.nlm.nih.gov/pubmed/35868559
http://dx.doi.org/10.1016/j.jbc.2022.102290