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Lack of immunogenicity of xenogeneic DNA from porcine biomaterials()()

BACKGROUND: Clinically useful biomaterials are derived from xenogeneic extracellular matrices, but extensive processes often used to remove all residual DNA are detrimental to their proper biological function. We hypothesized that deliberate and repeated injection of DNA extracted from clinically im...

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Detalles Bibliográficos
Autores principales: Record Ritchie, Rae D., Salmon, Sharon L., Hiles, Michael C., Metzger, Dennis W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418979/
https://www.ncbi.nlm.nih.gov/pubmed/36039075
http://dx.doi.org/10.1016/j.sopen.2022.07.005