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Dual specificity phosphatase 1 attenuates inflammation-induced cardiomyopathy by improving mitophagy and mitochondrial metabolism

OBJECTIVES: Dual specificity phosphatase 1 (DUSP1) is regarded as an anti-inflammatory factor in cardiovascular disorders. Mitophagy removes damaged mitochondria and thus promotes mitochondrial regeneration. We investigated whether DUSP1 could attenuate inflammation-induced cardiomyopathy by improvi...

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Detalles Bibliográficos
Autores principales: Tan, Ying, Zhang, Yue, He, Jing, Wu, Feng, Wu, Di, Shi, Nengxian, Liu, Weifeng, Li, Ziying, Liu, Wenqian, Zhou, Hao, Chen, Wenting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418987/
https://www.ncbi.nlm.nih.gov/pubmed/35944900
http://dx.doi.org/10.1016/j.molmet.2022.101567