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Enhanced efficacy in drug-resistant cancer cells through synergistic nanoparticle mediated delivery of cisplatin and decitabine

There are several limitations with monodrug cancer therapy, including poor bioavailability, rapid clearance and drug resistance. Combination therapy addresses these by exploiting synergism between different drugs against cancer cells. In particular, the combination of epigenetic therapies with conve...

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Detalles Bibliográficos
Autores principales: Parhizkar, M., Reardon, P. J. T., Harker, A. H., Browning, R. J., Stride, E., Pedley, R. B., Knowles, J. C., Edirisinghe, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419023/
https://www.ncbi.nlm.nih.gov/pubmed/36133040
http://dx.doi.org/10.1039/c9na00684b