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Biphasic effects of statins on neuron cell functions under oxygen–glucose deprivation and normal culturing conditions via different mechanisms

While there is a growing interest in the use of statins, HMG‐CoA reductase inhibitors, to treat neurodegenerative diseases, statins are associated with conflicting effects within the central nervous system (CNS) without clear evidence of the underlying mechanisms. This study systematically investiga...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Chen, Yun, Li, Ping, Chen, Yan, Yu, Danfang, Tan, Qian, Liu, Xiaoli, Guo, Zhenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419152/
https://www.ncbi.nlm.nih.gov/pubmed/36029136
http://dx.doi.org/10.1002/prp2.1001