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The multiple effects of REG1 deletion and SNF1 overexpression improved the production of S-adenosyl-l-methionine in Saccharomyces cerevisiae

BACKGROUND: Saccharomyces cerevisiae is often used as a cell factory for the production of S-adenosyl-l-methionine (SAM) for diverse pharmaceutical applications. However, SAM production by S. cerevisiae is negatively influenced by glucose repression, which is regulated by a serine/threonine kinase S...

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Detalles Bibliográficos
Autores principales: Chen, Hailong, Chai, Xiaoqin, Wang, Yan, Liu, Jing, Zhou, Guohai, Wei, Pinghe, Song, Yuhe, Ma, Lingman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419380/
https://www.ncbi.nlm.nih.gov/pubmed/36030199
http://dx.doi.org/10.1186/s12934-022-01900-7