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The multiple effects of REG1 deletion and SNF1 overexpression improved the production of S-adenosyl-l-methionine in Saccharomyces cerevisiae
BACKGROUND: Saccharomyces cerevisiae is often used as a cell factory for the production of S-adenosyl-l-methionine (SAM) for diverse pharmaceutical applications. However, SAM production by S. cerevisiae is negatively influenced by glucose repression, which is regulated by a serine/threonine kinase S...
Autores principales: | Chen, Hailong, Chai, Xiaoqin, Wang, Yan, Liu, Jing, Zhou, Guohai, Wei, Pinghe, Song, Yuhe, Ma, Lingman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419380/ https://www.ncbi.nlm.nih.gov/pubmed/36030199 http://dx.doi.org/10.1186/s12934-022-01900-7 |
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