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Zebrafish (Danio rerio) Is an Economical and Efficient Animal Model for Screening Potential Anti-cataract Compounds

PURPOSE: To develop a zebrafish cataract model for screening potential anti-cataract compounds. METHODS: Living zebrafish were anesthetized and exposed to ultraviolet-C (UV-C) irradiation at a dosage of 3250 mJ/cm(2)/d until they developed severe cataracts. These cataracts were graded based on photo...

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Detalles Bibliográficos
Autores principales: Liu, Chun-Fu, Ou-Yang, Yen, Huang, Ching-Ying, Jao, Shih-Wei, Kuo, Yu-Kai, Chen, Hung-Chi, Cheng, Shu-Chun, Wang, Nan-Kai, Chuang, Lan-Hsin, Chen, Yau-Hung, Chen, Wei-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419454/
https://www.ncbi.nlm.nih.gov/pubmed/35994266
http://dx.doi.org/10.1167/tvst.11.8.21