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Sustained Release of Tacrolimus From a Topical Drug Delivery System Promotes Corneal Reinnervation

PURPOSE: Corneal nerve fibers provide sensation and maintain the epithelial renewal process. Insufficient corneal innervation can cause neurotrophic keratopathy. Here, topically delivered tacrolimus is evaluated for its therapeutic potential to promote corneal reinnervation in rats. METHODS: A compa...

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Detalles Bibliográficos
Autores principales: Daeschler, Simeon C., Mirmoeini, Kaveh, Gordon, Tessa, Chan, Katelyn, Zhang, Jennifer, Ali, Asim, Feinberg, Konstantin, Borschel, Gregory H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419461/
https://www.ncbi.nlm.nih.gov/pubmed/35984668
http://dx.doi.org/10.1167/tvst.11.8.20