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Asymmetric bifunctional protein nanoparticles through redesign of self-assembly

Engineering oligomeric protein self-assembly is an attractive approach to fabricate nanostructures with well-defined geometries, stoichiometry and functions. The homodecamer Brucella Lumazine Synthase (BLS) is a highly stable and immunogenic protein nanoparticle (PNP). Here, we engineered the BLS pr...

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Detalles Bibliográficos
Autores principales: Sosa, Santiago, Rossi, Andrés H., Szalai, Alan M., Klinke, Sebastián, Rinaldi, Jimena, Farias, Ana, Berguer, Paula M., Nadra, Alejandro D., Stefani, Fernando D., Goldbaum, Fernando A., Bonomi, Hernán R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419478/
https://www.ncbi.nlm.nih.gov/pubmed/36134238
http://dx.doi.org/10.1039/c8na00375k