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Asymmetric bifunctional protein nanoparticles through redesign of self-assembly
Engineering oligomeric protein self-assembly is an attractive approach to fabricate nanostructures with well-defined geometries, stoichiometry and functions. The homodecamer Brucella Lumazine Synthase (BLS) is a highly stable and immunogenic protein nanoparticle (PNP). Here, we engineered the BLS pr...
Autores principales: | Sosa, Santiago, Rossi, Andrés H., Szalai, Alan M., Klinke, Sebastián, Rinaldi, Jimena, Farias, Ana, Berguer, Paula M., Nadra, Alejandro D., Stefani, Fernando D., Goldbaum, Fernando A., Bonomi, Hernán R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419478/ https://www.ncbi.nlm.nih.gov/pubmed/36134238 http://dx.doi.org/10.1039/c8na00375k |
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