Tyrosine carbon dots inhibit fibrillation and toxicity of the human islet amyloid polypeptide

Misfolding and aggregation of the human islet amyloid polypeptide (hIAPP) are believed to play key roles in the pathophysiology of type-II diabetes. Here, we demonstrate that carbon dots (C-dots) prepared from the amino acid tyrosine inhibit fibrillation of hIAPP, reduce hIAPP-induced cell toxicity...

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Detalles Bibliográficos
Autores principales: Bloch, Daniel Nir, Ben Zichri, Shani, Kolusheva, Sofiya, Jelinek, Raz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419576/
https://www.ncbi.nlm.nih.gov/pubmed/36133854
http://dx.doi.org/10.1039/d0na00870b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419576/
https://www.ncbi.nlm.nih.gov/pubmed/36133854
http://dx.doi.org/10.1039/d0na00870b

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