Nano-scale imaging of dual stable isotope labeled oxaliplatin in human colon cancer cells reveals the nucleolus as a putative node for therapeutic effect

Oxaliplatin shows a superior clinical activity in colorectal cancer compared to cisplatin. Nevertheless, the knowledge about its cellular distribution and the mechanisms responsible for the different range of oxaliplatin-responsive tumors is far from complete. In this study, we combined highly sensi...

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Detalles Bibliográficos
Autores principales: Legin, Anton A., Schintlmeister, Arno, Sommerfeld, Nadine S., Eckhard, Margret, Theiner, Sarah, Reipert, Siegfried, Strohhofer, Daniel, Jakupec, Michael A., Galanski, Mathea S., Wagner, Michael, Keppler, Bernhard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419577/
https://www.ncbi.nlm.nih.gov/pubmed/36131874
http://dx.doi.org/10.1039/d0na00685h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419577/
https://www.ncbi.nlm.nih.gov/pubmed/36131874
http://dx.doi.org/10.1039/d0na00685h

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