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Nano-scale imaging of dual stable isotope labeled oxaliplatin in human colon cancer cells reveals the nucleolus as a putative node for therapeutic effect
Oxaliplatin shows a superior clinical activity in colorectal cancer compared to cisplatin. Nevertheless, the knowledge about its cellular distribution and the mechanisms responsible for the different range of oxaliplatin-responsive tumors is far from complete. In this study, we combined highly sensi...
Autores principales: | Legin, Anton A., Schintlmeister, Arno, Sommerfeld, Nadine S., Eckhard, Margret, Theiner, Sarah, Reipert, Siegfried, Strohhofer, Daniel, Jakupec, Michael A., Galanski, Mathea S., Wagner, Michael, Keppler, Bernhard K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419577/ https://www.ncbi.nlm.nih.gov/pubmed/36131874 http://dx.doi.org/10.1039/d0na00685h |
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