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Adaptation by Type V-A and V-B CRISPR-Cas Systems Demonstrates Conserved Protospacer Selection Mechanisms Between Diverse CRISPR-Cas Types

Adaptation of clustered regularly interspaced short palindromic repeats (CRISPR) arrays is a crucial process responsible for the unique, adaptive nature of CRISPR-Cas immune systems. The acquisition of new CRISPR spacers from mobile genetic elements has previously been studied for several types of C...

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Detalles Bibliográficos
Autores principales: Wu, Wen Y., Jackson, Simon A., Almendros, Cristóbal, Haagsma, Anna C., Yilmaz, Suzan, Gort, Gerrit, van der Oost, John, Brouns, Stan J.J., Staals, Raymond H.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419969/
https://www.ncbi.nlm.nih.gov/pubmed/35833800
http://dx.doi.org/10.1089/crispr.2021.0150