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A Novel Levothyroxine Solution Results in Similar Bioavailability Whether Taken 30 or Just 15 Minutes Before a High-Fat High-Calorie Meal

BACKGROUND: Levothyroxine (LT4) sodium is a standard treatment for hypothyroidism. Its absorption and bioavailability when taken as a tablet have been shown to be significantly decreased with concomitant food ingestion. Therefore, LT4 formulations are recommended to be taken on an empty stomach, at...

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Detalles Bibliográficos
Autores principales: Ducharme, Murray, Scarsi, Claudia, Bettazzi, Elisa, Mautone, Giuseppe, Lewis, Yvette, Celi, Francesco S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419984/
https://www.ncbi.nlm.nih.gov/pubmed/35469428
http://dx.doi.org/10.1089/thy.2021.0604