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Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies

Early degeneration of basal forebrain cholinergic neurons contributes substantially to cognitive decline in Alzheimer’s disease. Evidence from preclinical models of neuronal injury and aging support a pivotal role for nerve growth factor (NGF) in neuroprotection, resilience, and cognitive function....

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Detalles Bibliográficos
Autores principales: Xhima, Kristiana, Markham-Coultes, Kelly, Hahn Kofoed, Rikke, Saragovi, H Uri, Hynynen, Kullervo, Aubert, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420023/
https://www.ncbi.nlm.nih.gov/pubmed/34919633
http://dx.doi.org/10.1093/brain/awab460