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Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies
Early degeneration of basal forebrain cholinergic neurons contributes substantially to cognitive decline in Alzheimer’s disease. Evidence from preclinical models of neuronal injury and aging support a pivotal role for nerve growth factor (NGF) in neuroprotection, resilience, and cognitive function....
Autores principales: | Xhima, Kristiana, Markham-Coultes, Kelly, Hahn Kofoed, Rikke, Saragovi, H Uri, Hynynen, Kullervo, Aubert, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420023/ https://www.ncbi.nlm.nih.gov/pubmed/34919633 http://dx.doi.org/10.1093/brain/awab460 |
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