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Epigenetic mechanisms and host factors impact ACE2 gene expression: Implications in COVID-19 susceptibility

BACKGROUND: The ACE2 protein acts as a gateway for SARS-CoV-2 in the host cell, playing an essential role in susceptibility to infection by this virus. Genetics and epigenetic mechanisms related to the ACE2 gene are associated with changes in its expression and, therefore, linked to increased suscep...

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Detalles Bibliográficos
Autores principales: Daniel, González, Paola, Ayala-Ramírez, Nancy, Gelvez, Fernando, Suarez-Obando, Beatriz, Ariza, Zulema, Ruiz, Julieth, Arcila, Claudia, Cardozo, Adriana, Rojas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pontificia Universidad Javeriana. Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420046/
https://www.ncbi.nlm.nih.gov/pubmed/36038007
http://dx.doi.org/10.1016/j.meegid.2022.105357