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The neurophysiological effect of NMDA-R antagonism of frontotemporal lobar degeneration is conditional on individual GABA concentration

There is a pressing need to accelerate therapeutic strategies against the syndromes caused by frontotemporal lobar degeneration, including symptomatic treatments. One approach is for experimental medicine, coupling neurophysiological studies of the mechanisms of disease with pharmacological interven...

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Detalles Bibliográficos
Autores principales: Perry, Alistair, Hughes, Laura E., Adams, Natalie, Naessens, Michelle, Murley, Alexander G., Rouse, Matthew A., Street, Duncan, Jones, P. Simon, Cope, Thomas E., Kocagoncu, Ece, Rowe, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420128/
https://www.ncbi.nlm.nih.gov/pubmed/36030249
http://dx.doi.org/10.1038/s41398-022-02114-6