Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c(+) dendritic cells

Inflammasomes are multiprotein platforms responsible for the release of pro-inflammatory cytokines interleukin (IL)-1β and IL-18. Mouse studies have identified inflammasome activation within dendritic cells (DC) as pivotal for driving tubulointerstitial fibrosis and inflammation, the hallmarks of ch...

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Detalles Bibliográficos
Autores principales: Giuliani, Kurt T. K., Grivei, Anca, Nag, Purba, Wang, Xiangju, Rist, Melissa, Kildey, Katrina, Law, Becker, Ng, Monica S., Wilkinson, Ray, Ungerer, Jacobus, Forbes, Josephine M., Healy, Helen, Kassianos, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420140/
https://www.ncbi.nlm.nih.gov/pubmed/36030251
http://dx.doi.org/10.1038/s41419-022-05191-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420140/
https://www.ncbi.nlm.nih.gov/pubmed/36030251
http://dx.doi.org/10.1038/s41419-022-05191-z

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