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Design, Synthesis, Docking Study, and Biological Evaluation of 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbohydrazide Derivatives as Anti-HIV-1 and Antibacterial Agents.

BACKGROUND: The emergence of drug resistance to the existing antibacterial and anti-HIV-1 therapeutics has posed an urgent medical need to develop new molecules. We describe in this regard, a series of novel N'-arylidene-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbohydrazide derivatives with ant...

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Detalles Bibliográficos
Autores principales: Abdollahi, Omid, Mahboubi, Arash, Hajimahdi, Zahra, Zarghi, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brieflands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420229/
https://www.ncbi.nlm.nih.gov/pubmed/36060913
http://dx.doi.org/10.5812/ijpr-126562