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Synthesis, Biological Evaluation, and Molecular Modeling Studies of New 8-methyl-4-oxo-1,4-dihydroquinoline-3-carbohydrazides as Potential Anti-HIV Agents

BACKGROUND: The development of a highly safe and potent scaffold is a significant challenge in anti-HIV drug discovery. OBJECTIVES: This study aimed at developing a novel series of anti-HIV agents based on HIV integrase inhibitor pharmacophores. METHODS: A novel series of 8-methyl-4-oxo-1,4-dihydroq...

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Detalles Bibliográficos
Autores principales: Alemi, Mehrdad, Kamali, Fatemeh, Vahabpour Roudsari, Rouhollah, Hajimahdi, Zahra, Zarghi, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brieflands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420234/
https://www.ncbi.nlm.nih.gov/pubmed/36060911
http://dx.doi.org/10.5812/ijpr-123962