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Synthesis, Biological Evaluation, and Molecular Modeling Studies of New 8-methyl-4-oxo-1,4-dihydroquinoline-3-carbohydrazides as Potential Anti-HIV Agents
BACKGROUND: The development of a highly safe and potent scaffold is a significant challenge in anti-HIV drug discovery. OBJECTIVES: This study aimed at developing a novel series of anti-HIV agents based on HIV integrase inhibitor pharmacophores. METHODS: A novel series of 8-methyl-4-oxo-1,4-dihydroq...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Brieflands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420234/ https://www.ncbi.nlm.nih.gov/pubmed/36060911 http://dx.doi.org/10.5812/ijpr-123962 |