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Connecting telomere maintenance and regulation to the developmental origin and differentiation states of neuroblastoma tumor cells
A cardinal feature that distinguishes clinically high-risk neuroblastoma from low-risk tumors is telomere maintenance. Specifically, neuroblastoma tumors with either active telomerase or alternative lengthening of telomeres exhibit aggressive growth characteristics that lead to poor outcomes, wherea...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420296/ https://www.ncbi.nlm.nih.gov/pubmed/36030273 http://dx.doi.org/10.1186/s13045-022-01337-w |