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Stabilization of DEPTOR sensitizes hypopharyngeal cancer to radiotherapy via targeting degradation
The use of radiotherapy for hypopharyngeal cancer (HC) treatment is increasing, and it is currently the primary treatment option for this cancer. However, radioresistance occurs in a proportion of patients. Here, we found that radiation increased proteasomal gene expression and that proteasome assem...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420345/ https://www.ncbi.nlm.nih.gov/pubmed/36090478 http://dx.doi.org/10.1016/j.omto.2022.08.002 |