Stabilization of DEPTOR sensitizes hypopharyngeal cancer to radiotherapy via targeting degradation

The use of radiotherapy for hypopharyngeal cancer (HC) treatment is increasing, and it is currently the primary treatment option for this cancer. However, radioresistance occurs in a proportion of patients. Here, we found that radiation increased proteasomal gene expression and that proteasome assem...

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Detalles Bibliográficos
Autores principales: Wang, Xuecen, Cao, Zhirui, Yue, Xin, Liu, Tingyu, Wen, Gesi, Jiang, Dongmei, Wu, Weijian, Le, Liyuan, Wang, Yan, Wang, Chengtao, Wang, Ziyang, Jin, Meng, Zhu, Meiyan, He, Shasha, Zhang, Xiaoyue, Bu, Xianzhang, Liu, Ran-yi, Peng, Zhenwei, Chen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420345/
https://www.ncbi.nlm.nih.gov/pubmed/36090478
http://dx.doi.org/10.1016/j.omto.2022.08.002

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