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Intestinal Inflammation Promotes MDL-1(+) Osteoclast Precursor Expansion to Trigger Osteoclastogenesis and Bone Loss

BACKGROUND & AIMS: Inflammatory bowel disease (IBD) is characterized by severe gastrointestinal inflammation, but many patients experience extra-intestinal disease. Bone loss is one common extra-intestinal manifestation of IBD that occurs through dysregulated interactions between osteoclasts and...

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Detalles Bibliográficos
Autores principales: Peek, Christopher T., Ford, Caleb A., Eichelberger, Kara R., Jacobse, Justin, Torres, Teresa P., Maseda, Damian, Latour, Yvonne L., Piazuelo, M. Blanca, Johnson, Joshua R., Byndloss, Mariana X., Wilson, Keith T., Rathmell, Jeffrey C., Goettel, Jeremy A., Cassat, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420375/
https://www.ncbi.nlm.nih.gov/pubmed/35835390
http://dx.doi.org/10.1016/j.jcmgh.2022.07.002