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Intestinal Inflammation Promotes MDL-1(+) Osteoclast Precursor Expansion to Trigger Osteoclastogenesis and Bone Loss
BACKGROUND & AIMS: Inflammatory bowel disease (IBD) is characterized by severe gastrointestinal inflammation, but many patients experience extra-intestinal disease. Bone loss is one common extra-intestinal manifestation of IBD that occurs through dysregulated interactions between osteoclasts and...
Autores principales: | Peek, Christopher T., Ford, Caleb A., Eichelberger, Kara R., Jacobse, Justin, Torres, Teresa P., Maseda, Damian, Latour, Yvonne L., Piazuelo, M. Blanca, Johnson, Joshua R., Byndloss, Mariana X., Wilson, Keith T., Rathmell, Jeffrey C., Goettel, Jeremy A., Cassat, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420375/ https://www.ncbi.nlm.nih.gov/pubmed/35835390 http://dx.doi.org/10.1016/j.jcmgh.2022.07.002 |
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