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Enhanced sciatic nerve regeneration by relieving iron-overloading and organelle stress with the nanofibrous P(MMD-co-LA)/DFO conduits

Wallerian degeneration after peripheral nerve injury (PNI), that is, the autonomous degeneration of distal axons, leads to an imbalance of iron homeostasis and easily induces oxidative stress caused by iron overload. Inspired by the process of nerve degeneration and regeneration, the design of a fun...

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Detalles Bibliográficos
Autores principales: Han, Lei, Dong, Xianzhen, Qiu, Tong, Dou, Zhaona, Wu, Lin, Dai, Honglian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420382/
https://www.ncbi.nlm.nih.gov/pubmed/36042854
http://dx.doi.org/10.1016/j.mtbio.2022.100387