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NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma
BACKGROUND: T-cell receptor-engineered T-cell therapies have achieved promising response rates against synovial sarcoma in clinical trials, but their applicability is limited owing to the HLA matching requirement. Chimeric antigen receptor (CAR) can redirect primary T cells to tumor-associated antig...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420389/ https://www.ncbi.nlm.nih.gov/pubmed/35998437 http://dx.doi.org/10.1016/j.tranon.2022.101521 |