Generating transcriptional regulatory networks from time-ordered stem cell differentiation RNA sequencing data

We describe steps to 1) identify ascending and descending monotonic key genes from time-ordered stem cell differentiation expression data, 2) construct time-ordered transcriptional regulatory networks, and 3) infer the involvement of transcription factors along the differentiation process. For compl...

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Detalles Bibliográficos
Autores principales: Tsai, Yu-Shuen, Chang, Yao-Ming, Lim, Yang-Mooi, Cheong, Soon-Keng, Chung, I-Fang, Wong, Chee-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420390/
https://www.ncbi.nlm.nih.gov/pubmed/36042881
http://dx.doi.org/10.1016/j.xpro.2022.101541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420390/
https://www.ncbi.nlm.nih.gov/pubmed/36042881
http://dx.doi.org/10.1016/j.xpro.2022.101541

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