Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of liver pathologies. However, no medical treatment has been approved for the treatment of NAFLD. In our previous study, we found that PKLR could be a potential target for treatment of NALFD. Here, we investigated the...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng, Shi, Mengnan, Kim, Woonghee, Arif, Muhammad, Klevstig, Martina, Li, Xiangyu, Yang, Hong, Bayram, Cemil, Bolat, Ismail, Tozlu, Özlem Özdemir, Hacımuftuoglu, Ahmet, Yıldırım, Serkan, Sebhaoui, Jihad, Iqbal, Shazia, Wei, Yongjun, Shi, Xiaojing, Nielsen, Jens, Turkez, Hasan, Uhlen, Mathias, Boren, Jan, Mardinoglu, Adil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420484/
https://www.ncbi.nlm.nih.gov/pubmed/35988463
http://dx.doi.org/10.1016/j.ebiom.2022.104214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420484/
https://www.ncbi.nlm.nih.gov/pubmed/35988463
http://dx.doi.org/10.1016/j.ebiom.2022.104214

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