Coupling live-cell imaging and in situ isolation of the same single cell to profile the transient states of predicted drug-tolerant cells

Cell response variability is a starting point in cancer drug resistance that has been difficult to analyze because the tolerant cell states are short lived. Here, we present fate-seq, an approach to isolate single cells in their transient states of drug sensitivity or tolerance before profiling. The...

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Detalles Bibliográficos
Autores principales: Bian, Benjamin, Paquet, Agnès, Arguel, Marie-Jeanne, Meyer, Mickael, Peyre, Ludovic, Chalabi, Asma, Péré, Marielle, Lebrigand, Kevin, Waldmann, Rainer, Barbry, Pascal, Hofman, Paul, Roux, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420533/
https://www.ncbi.nlm.nih.gov/pubmed/36042886
http://dx.doi.org/10.1016/j.xpro.2022.101600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420533/
https://www.ncbi.nlm.nih.gov/pubmed/36042886
http://dx.doi.org/10.1016/j.xpro.2022.101600

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