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Coupling live-cell imaging and in situ isolation of the same single cell to profile the transient states of predicted drug-tolerant cells
Cell response variability is a starting point in cancer drug resistance that has been difficult to analyze because the tolerant cell states are short lived. Here, we present fate-seq, an approach to isolate single cells in their transient states of drug sensitivity or tolerance before profiling. The...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420533/ https://www.ncbi.nlm.nih.gov/pubmed/36042886 http://dx.doi.org/10.1016/j.xpro.2022.101600 |