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Fluoride Exposure Suppresses Proliferation and Enhances Endoplasmic Reticulum Stress and Apoptosis Pathways in Hepatocytes by Downregulating Sirtuin-1

OBJECTIVE: To explore the function and mechanism of Sirt-1 in fluorine-induced liver injury. METHOD: Fluorosis rats were first established. The fluorine content, pathological structure, collagen fibers, and fibrosis in liver tissues were tested through the fluoride ion selective electrode method, H&...

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Detalles Bibliográficos
Autores principales: Yu, Yanlong, Li, Ling, Yu, Wenfeng, Guan, Zhizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420589/
https://www.ncbi.nlm.nih.gov/pubmed/36046439
http://dx.doi.org/10.1155/2022/7380324