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5-HT(7) receptor-dependent intestinal neurite outgrowth contributes to visceral hypersensitivity in irritable bowel syndrome
Irritable bowel syndrome (IBS) is characterized by visceral hypersensitivity (VH) associated with abnormal serotonin/5-hydroxytryptamine (5-HT) metabolism and neurotrophin-dependent mucosal neurite outgrowth. The underlying mechanisms of VH remain poorly understood. We investigated the role of 5-HT(...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420680/ https://www.ncbi.nlm.nih.gov/pubmed/35585132 http://dx.doi.org/10.1038/s41374-022-00800-z |